Semaglutide
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Semaglutide

Price range: $59.00 through $99.00

Semaglutide is a high-purity, synthetic peptide and long-acting GLP-1 (glucagon-like peptide-1) analog designed for advanced research applications. Known for its enhanced stability and extended half-life, semaglutide is a preferred compound in GLP-1 receptor and metabolic regulation studies. Our semaglutide is >98% pure (HPLC verified) and supplied as a sterile lyophilized powder for maximum stability during storage and transport. Check out our Bulk Semaglutide Options!

2 - 5 10%
6 - 10 20%
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Description

What is Semaglutide?
Semaglutide is a synthetic 31-amino acid polypeptide analog of human glucagon-like peptide-1 (GLP-1), sharing 94% structural homology with native GLP-1(7-37). This research-grade peptide functions as a selective GLP-1 receptor agonist and features three key structural modifications: an amino acid substitution at position 8 (alanine to α-aminoisobutyric acid), a substitution at position 34 (lysine to arginine), and lipidation at lysine-26 with a C18 fatty diacid chain via a gamma-glutamic acid spacer. These modifications significantly extend the peptide’s half-life and enhance its receptor binding affinity, making semaglutide a valuable tool for researchers studying incretin-based metabolic pathways and GLP-1 receptor mechanisms.
Research Applications & Areas of Study
Scientists and research institutions utilize semaglutide in laboratory studies examining:
  • GLP-1 receptor activation and downstream signaling cascades
  • Glucose-dependent insulin secretion mechanisms in pancreatic beta cells
  • Glucagon suppression pathways and glycemic regulation
  • Appetite regulation and hypothalamic satiety signaling
  • Gastric emptying modulation and gastrointestinal motility
  • Cardiovascular effects of GLP-1 receptor agonism
  • Neuroprotective mechanisms and brain GLP-1 receptor distribution
  • Long-acting peptide analog design and pharmacokinetic optimization
  • Comparative incretin studies (GLP-1 vs. dual GIP/GLP-1 agonists)
  • Metabolic pathway modulation in obesity and diabetes research models
The structural modifications of semaglutide—particularly the α-aminoisobutyric acid at position 8 and C18 fatty acid conjugation—provide resistance to dipeptidyl peptidase-4 (DPP-4) degradation and enable albumin binding, contributing to its extended duration of action in research protocols.
Purity & Quality Assurance
Every batch of Encompass Peptides semaglutide undergoes rigorous third-party testing to verify 99%+ purity. Our commitment to research integrity means:
  • HPLC and Mass Spectrometry Testing: Each batch is analyzed using high-performance liquid chromatography and mass spectrometry to confirm molecular identity, purity, and structural integrity
  • Certificate of Analysis (COA): Complete documentation included with every shipment, detailing purity percentages, testing methods, batch numbers, and verification dates
  • Proper Storage Protocols: Lyophilized peptide stored under controlled conditions to maintain stability and prevent degradation
  • Veteran-Owned Quality Standards: As a veteran-owned business, we prioritize precision, reliability, and transparency in every product we deliver to the research community
Packaging & Shipping Details
  • Precision Packaging: Sealed in sterile vials with tamper-evident caps to ensure product integrity during transit
  • Fast Fulfillment: Orders ship within 24 hours of purchase to support time-sensitive research protocols
  • Nationwide Availability: Ships to all 50 US states with no regulatory restrictions
  • Discreet Shipping: Professional packaging with no external product identification
  • Temperature Control: Shipped with appropriate cooling materials to maintain peptide stability throughout delivery
Storage Recommendations
For optimal stability and longevity:
  • Lyophilized (Unreconstituted): Store at -20°C (freezer) for up to 24 months; keep desiccated
  • Reconstituted Solution: Store at 2-8°C (refrigerator) for up to 30 days; avoid repeated freeze-thaw cycles
  • Light Protection: Keep vials in original packaging away from direct light exposure to prevent photodegradation
  • Contamination Prevention: Use sterile technique when handling and reconstituting; maintain aseptic conditions
Why Choose Encompass Peptides?
  • ✓ Veteran-Owned Business: Built on principles of integrity, precision, and service excellence
  • ✓ 99%+ Purity Guarantee: Every batch tested and verified by independent third-party laboratories
  • ✓ COA Documentation: Complete transparency with comprehensive testing documentation
  • ✓ Fast Shipping: <24-hour fulfillment to support your research timeline and project deadlines
  • ✓ Dedicated Support: Expert assistance for researchers, institutions, and laboratories
  • ✓ US-Based: Reliable domestic sourcing and shipping to all 50 states
Related Research Peptides
Researchers studying semaglutide often explore complementary compounds for comparative analysis:
  • Tirzepatide – Dual GIP/GLP-1 receptor agonist for advanced metabolic research
  • Retatrutide – Triple agonist (GIP/GLP-1/glucagon) for comprehensive metabolic studies
  • Liraglutide – GLP-1 receptor agonist with shorter half-life for comparative research
  • BPC-157 – Tissue repair and healing research peptide
  • CJC-1295 – Growth hormone releasing hormone analog
Comparative Research Considerations
Semaglutide’s unique structural modifications make it particularly valuable for:
  • Stability Studies: Extended half-life compared to native GLP-1 enables longer observation periods
  • Receptor Binding Research: Enhanced affinity allows for detailed receptor interaction studies
  • Pharmacokinetic Analysis: Albumin binding properties provide insights into peptide delivery optimization
  • Comparative Incretin Studies: Direct comparison with dual agonists (tirzepatide) or triple agonists (retatrutide)
For Research Use Only
This product is intended strictly for in-vitro research and laboratory applications by qualified researchers and institutions. Not for human consumption, clinical use, or veterinary applications. Researchers should follow all applicable institutional guidelines, safety protocols, and regulatory requirements.
Order Your Semaglutide Research Peptide Today
Advance your metabolic and incretin research with premium-grade semaglutide from Encompass Peptides. Every order includes complete COA documentation and ships within 24 hours to all 50 US states. Questions about bulk pricing or volume discounts for larger research orders? Contact our dedicated research support team for customized solutions.

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